Scientific Studies

Okashi T, Kani T, Isozaki A, Nishida A, Shintani H, Tokumoto T, Ishizu E, Kuwahara Y, Kani, M: Remineralization of artificial caries lesions by Hydroxy­apatite. I Dent Health 41, 214 – 223 (1991).

Roughness reduction

Mielczarek et.al, The effect of nano-hydroxyapatite toothpaste on enamel surface remineralization. An in vitro study, American Journal of Dentistry 27, 287-290 (2014).

Anti-caries

Kuilong L, Xiangcai M, Jiuxing Z, Xingyi L, Xingyi L, Meiling Z: Inhibitory Effect of Synthetic Nano-Hydroxyapatite on Dental Caries. Key Engineering Materials 336 – 338, 1538 – 1541 (2007).

Fluoride & Hydroxyapatite

M. Y. Kim et. al., Key Engineering Materials  330 – 332, 1347 – 1350 (2007).

Reduction of caries in children

Kani T, Kani M, Isozaki A, Shintani H, Ohashi T, Tokumoto T: Effect to apatite-containing dentifrices on dental caries in school children. I Dent Health 39, 104 – 109 (1989).

Brightening & gloss

Niwa M, Sato T, Li W, Aoki H: Polishing and Whitening Properties of Tooth­paste,
J Mater Sci, Mater Med 12, 277 – 81 (2001).

Sealing enamel

Kawamata H, Nishio M, Fujita K, Ishizaki T, Hayman R, Ikemi T: Posterpresentation 82nd General Session & Exhibition of the IADR / March 2004

Delayed plaque formation

Nishio M, Kawamata H, Fujita K, Ishizaki T, Hayman R, Ikemi T: A new enamel restoring agent for use after PMTC. Posterpresentation 82nd General Session & Exhibition of the IADR / March 2004.